J Sci Discov (2020); 4(2):jsd20018; DOI:10.24262/jsd.4.2.20018; Received June 02rd, 2020,Revised July 18th, 2020, Accepted July 31st, 2020, Published August 12rd, 2020.
Estimation of Oxygen Pressure in Arterial Blood from Pulse Oximetry: A Useful Out-of-hospital Tool
Manuel Piñero-Zapata1, 3,Alejandro Piñero-Garcia2,Amelia Margarita Canovas-Miralles3,Maria Eva Legaz-Moreno3
1Nursing Faculty. San Antonio Catholic University of Murcia. Spain.
2Higher school of telecommunications. Polytechnic University of Cartagena. Cartagena. Spain.
3Mobile Emergencies Unit. Gerencia de Urgencias y Emergencias 061. Servicio Murciano de Salud. Murcia. Spain.
* Correspondence: Manuel Piñero-Zapata,Nursing Faculty. San Antonio Catholic University of Murcia. Spain..E-mail:manuelpinerozapata@gmail.com
Abstract
Background In out-of-hospital emergency, there are obvious limitations for therapeutic decision-making due to the lack of complementary tests that are available in the hospital environment, including the value of arterial oxygen pressure (PaO2) using arterial blood gas as It helps in assessing the severity of patients with Acute Respiratory Failure.
Methods Obtain PaO2 equivalency values from integer SaO2 values on the measurement scale between 1% and 100%, and set the SaO2/FiO2 intervals associated with severity levels in acute respiratory failure (ARF) hypoxemic. Mathematical analysis by inversion of the function of the Hemoglobin Dissociation Curve at physiological values of pH=7.4 and Tª=37°C, to obtain the equivalent values of PO2 in arterial blood from integer values of SpO2 obtained by pulse oximetry.
Results A correspondence table was obtained between SaO2 and PaO2 as well as the SaO2/FiO2 intervals equivalent to those of PaO2/FiO2 according to severity levels in patients with hypoxemic ARF with FiO2=21%.
Conclusions SpO2, in the absence of PaO2, is useful in establishing the severity of patients with hypoxemic ARF in emergency situations.
Keywords: Transcutaneous Oximetry; Respiratory Insufficiency; Emergencies
Conflicts Of Interest
None
Acknowledgments
None
References
- Merlani P, Garnerin P, Diby M, Ferring M, Ricou B. Quality Improvement Report: Linking guideline to regular feedback to increase appropriate requests for clinical tests: blood gas analysis in intensive care. BMJ. 2001;323(7313):620–
- O’Driscoll BR, Howard LS, Earis J, Mak V, Bajwah S, Beasley R, et al. BTS guideline for oxygen use in adults in healthcare and emergency settings. Vol. 72, Thorax. BMJ Publishing Group; 2017. p. i1-90.
- Kirby RR, Downs JB, Civetta JM, Modell JH, Dannemiller FJ, Klein EF, et al. High level positive end expiratory pressure (PEEP) in acute respiratory insufficiency. Chest. 1975 Feb 1;67(2):156–
- Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, Fan E, et al. Acute respiratory distress syndrome: The Berlin definition. JAMA – J Am Med Assoc. 2012;307(23):2526–
- Toffaletti JG, Rackley CR. Monitoring Oxygen Status. In: Advances in Clinical Chemistry. Academic Press Inc.; 2016. p. 103–
- Hess D. Detection and monitoring of hypoxemia and oxygen therapy. Respir Care. 2000;45(1):65–
- Ali-Munive A, Rodriguez P, Gomez S, Arce AM, Rodriguez E. Correlacion entre pulsioximetria y saturacion arterial de oxigeno en pacientes en cuidado intensivo. Acta méd colomb. 2002;27:162–
- Candela-Zamora MD, Fernández-Pérez C, Río-Gallegos F, Jiménez de Diego L, Pontón-Soriano C, Alvarez Alvarez MM. PO 2 basal en pacientes con patrón respiratorio ineficaz en sala de agudos de urgencia. Emergencias. 1999;11(2):114–
- Cinesi-Gómez C, García-García P, López-Pelayo I, Giménez JI, González-Torres LM, Bernal-Morell E. Correlación entre la saturación de oxihemoglobina por pulsioximetría y la presión arterial de oxígeno en pacientes con insuficiencia respiratoria aguda. Rev Clin Esp. 2017;217(9):522–
- Bilan N, Dastranji A, Ghalehgolab Behbahani A. Comparison of the Spo 2 /Fio 2 Ratio and the Pao 2 /Fio 2 Ratio in Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome . J Cardiovasc Thorac Res. 2015;7(1):28–
- Roughton FJ, Severinghaus JW. Accurate determination of O2 dissociation curve of human blood above 98.7 percent saturation with data on O2 solubility in unmodified human blood from 0 degrees to 37 degrees C. J Appl Physiol. 1973;35(6):861–
- Morgan TJ. The oxyhaemoglobin dissociation curve in critical illness. Crit Care Resusc. 1999;1(1):93–
- Khee-Shing ML. Configuration of the hemoglobin oxygen dissociation curve demystified: a basic mathematical proof for medical and biological sciences undergraduates. Adv Physiol Educ. 2007;31:198–
- Hill AV. The possible effects of the aggregation of the molecules of haemoglobin on its oxygen dissociation curve – J Physiol. 1910;40(4).
- Martín Escribano P. Notas clínicas. Arch Bronconeumol. 1974;10(1):33–
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